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| 三种常用氨基甲酸酯类农药人工抗原合成方法的设计与优选 |
| Design and Selection of Synthesis Methods of Artificial Antigens for Three Frequently-used N-methylcarbamate Pesticides |
| Received:October 10, 2013 |
| DOI： |
| 中文关键词: 氨基甲酸酯类农药;甲萘威;克百威;涕灭威;半抗原;人工抗原;合成方法 |
| 英文关键词: N-methylcarbamate pesticides;carbaryl;carbofuran;aldicarb;hapten;artificial antigen;synthesis methods |
| 基金项目:公益性行业(农业)科研专项经费项目(201203094-2) |
| Author Name | Affiliation | E-mail | | QU Qiao-yu | Agro-Environmental Protection Institute, Ministry of Agriculture, Tianjin 300191, China | | | CHEN Shan-shan | Agro-Environmental Protection Institute, Ministry of Agriculture, Tianjin 300191, China | | | LIU Xiao-wei | Agro-Environmental Protection Institute, Ministry of Agriculture, Tianjin 300191, China | xwliu2006@163.com |
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| 中文摘要: |
| 农药人工抗原的合成直接影响制备抗体的质量,是建立农药分子特异性强、灵敏度高的免疫分析方法的关键。本文综述了国内外对于氨基甲酸酯类广泛使用的3种农药甲萘威、克百威、涕灭威人工抗原合成过程中的农药分子半抗原的设计原则、合成方法,人工抗原的设计、优选及影响因素等方面的研究进展。 |
| 英文摘要: |
| Synthesis of artificial antigens of pesticides directly influences the quality of the antibodies,and is critical in the format of particular and sensitive immunology assay. The progress of the design principle and synthesis methods of haptens of three kinds of N-methylcarbamate pesticides including carbaryl,carbofuran,aldicarb were introduced in this paper. Furthermore,the design and selection of synthesis methods for artificial antigens and the influencing factors of the synthesis were also presented. |
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