|
| 腐殖质调控农田土壤细菌耐药传播扩散的作用机制研究进展 |
| Role of humus in regulating the proliferation of bacterial antibiotic resistance in agricultural soils: a review |
| 投稿时间：2024-11-05 |
| DOI：10.13254/j.jare.2024.0876 |
| 中文关键词: 腐殖质，农田土壤，耐药基因，调控，传播扩散 |
| 英文关键词: humus, agricultural soil, antibiotics resistance gene, regulation, proliferation |
| 基金项目:中国农业科学院青年创新计划项目（Y2023QC32）；国家资助博士后研究人员计划项目（GZC20241952） |
|
| 摘要点击次数: 211 |
| 全文下载次数: 262 |
| 中文摘要: |
| 由于抗生素在畜禽养殖业中广泛使用，加剧了农业环境细菌耐药问题。特别是有机肥资源化的滥用加剧了农田土壤中抗生素耐药基因（ARGs）污染。除有机肥携带大量ARGs直接被引入到农田环境，农田腐殖质也被认为是影响土壤ARGs定殖和增殖的关键因素。然而，现阶段关于腐殖质对农田系统ARGs传播扩散的促进/抑制作用和机制缺乏系统的认知。对此，本文综述了农田系统中腐殖质对ARGs传播扩散的正向/负向调控作用，梳理了腐殖质调控ARGs传播扩散的影响因素，例如土壤与腐殖质自身物化特性，土壤微生物组构成等，并厘清了腐殖质通过吸附作用、群落重塑及介导电子传递等方式调控ARGs定殖扩散的作用路径与关键机制。此外，本文提出构建电化学装置，深入探究腐殖质干预根际耐药变化的微生物群落效应，明确介导植物-微生物协同调节反馈作用，并以此发展有效遏制农田细菌耐药蔓延关键技术的建议。 |
| 英文摘要: |
| Due to the widespread use of antibiotics in livestock and poultry farming, the problem of bacterial resistance in the agricultural environment has been exacerbated. In particular, the misuse of organic fertilizer resourcefulness has aggravated the contamination of antibiotic resistance genes（ARGs）in farmland soils. Beyond the direct introduction of abundant ARGs carried by organic fertilizers into the farmland environment, farmland humus is also regarded as a critical factor influencing the colonization and proliferation of soil ARGs. However, a systematic understanding of the promoting or inhibiting effects and mechanisms of humus on ARGs dissemination in farmland systems is currently lacking. Herein, we reviewed the positive and negative regulatory roles of humus in ARGs dissemination within farmland systems, and collated influencing factors such as the physicochemical properties of soil and humus and the composition of the soil microbiome. We further clarified the pathways and key mechanisms by which humus regulates ARGs colonization and diffusion through adsorption, community reshaping, and mediating electron transfer. Moreover, we propose constructing electrochemical devices to deeply investigate the microbial community effects of humus intervention on rhizosphere resistance changes, to define the feedback mediated by plant – microbe co-regulation, and thereby to develop critical technologies for effectively curbing the spread of bacterial resistance in farmland. |
| HTML
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
