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| Composition profile and environmental risks of antibiotics in sediments of Nansi Lake |
| Received:August 13, 2023 |
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| KeyWord:antibiotic;ecological risk;resistance development risk;sediment;Nansi Lake |
| Author Name | Affiliation | E-mail | | SANG Wencai | School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China | | | LI Jinyang | CCCC TDC Southern Communication Construction Co., Ltd., Shenzhen 518100, China | | | LIN Yanran | School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China | | | LI Shiwei | School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China | | | GAO Weidong | School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China | | | HAN Xuemei | School of Water Conservancy and Environment, University of Jinan, Jinan 250022, China | stu_hanxm@ujn.edu.cn |
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| Abstract: |
| To ensure the ecological security of Nansi Lake and the health of the surrounding residents, antibiotics categorized into macrolides, tetracyclines, quinolones, β-lactams, sulfonamides, and chloramphenicol antibiotics were determined in the sediments of the lake before and after the flood. The composition profiles and potential environmental risks of the antibiotics were also analyzed and evaluated. The results showed that the total concentrations of antibiotics ranged from 2.72 ng·g-1 to 276.07 ng·g-1. The antibiotics with high average concentration were mainly classified as quinolones, including ofloxacin（11.67 ng·g-1）, enrofloxacin（4.96 ng·g-1）, ciprofloxacin （3.80 ng·g-1）, and norfloxacin（3.60 ng·g-1）, and tetracyclines, including oxytetracycline（6.40 ng·g-1）and chloromycin（2.34 ng·g-1）. Moreover, high detection rates were found for some macrolide antibiotics, such as lincomycin and roxithromycin, which had a detection rate of 100%. There was a significant difference in antibiotic profiles between after and before the flood（Adonis test, P＜0.01）. Both the concentration and number of antibiotics were higher after the flood（48.21 ng·g-1, 27 species）than before the flood（32.08 ng ·g-1, 23 species）. There was no significant difference in antibiotic profile between the superior lake and subordinate lake, although large variation was observed among different sampling sites. Based on the risk quotients, ofloxacin, ciprofloxacin, oxytetracycline, and lincomycin were at high ecological risk and high resistance development risk. Some other antibiotics such as norfloxacin and chloramphenicol might pose a high resistance development risk. |
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