| 贾斌,庾旸,马海川,陈以芹,李娟英.我国长三角地区淡水池塘养殖水产品中抗生素残留及对人体暴露的贡献评价[J].农业环境科学学报,2022,41(2):238-245. |
| 我国长三角地区淡水池塘养殖水产品中抗生素残留及对人体暴露的贡献评价 |
| Antibiotic residues and human exposure evaluation in freshwater aquaculture products from Yangtze River Delta， China |
| 投稿时间：2021-05-25 |
| DOI：10.11654/jaes.2021-0607 |
| 中文关键词: 抗生素 淡水养殖水产品 尿液抗生素 人体暴露 饮食贡献 |
| 英文关键词: antibiotic freshwater cultured product urinary antibiotics body burden dietary contribution estimation |
| 基金项目:上海市科委科技基金项目（18050502100） |
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| 中文摘要: |
| 为探究我国长三角地区淡水养殖水产品中抗生素残留特征及食用风险，于2019年7—10月采集上海、浙江、江苏、安徽、福建等5个地区淡水养殖池塘3类水产品（鱼类、虾类、蟹类），使用高效液相色谱-串联质谱法（LC-MS/MS）检测水产品中的9种常见抗生素，并根据人体可接受的每日摄入量（ADI）及养殖水产品消费对抗生素暴露的贡献率（CR）分别评价食用安全性和暴露风险。结果表明：9种抗生素均有检出，检出频率范围为38.1%~90.5%，浓度范围为nd~25.25 ng·g-1；估算的每日摄入量（EDI）远低于ADI；Σ抗生素的贡献率范围为<0.01%~29.77%。研究表明，水产品摄入不会对人体健康构成抗生素暴露风险，但食用水产品时，喹诺酮类和大环内酯类抗生素的摄入应引起关注。 |
| 英文摘要: |
| This study aimed to investigate antibiotic contamination in freshwater cultured products in the Yangtze River Delta region and the risk of antibiotic exposure through consumption. Three types of products(fish, shrimp, and crab) from freshwater aquaculture ponds in five regions of China(Shanghai, Zhejiang, Jiangsu, Anhui, and Fujian) were collected from July to October 2019. High-performance liquid chromatography-tandem mass spectrometry(LC-MS/MS) was used to detect nine types of antibiotics in the samples. The human acceptable daily intake(ADI) and the contribution of cultured aquatic product consumption to antibiotic exposure contribution ratio(CR) were used to evaluate the exposure risk. All nine antibiotics were detected and the detection frequency ranged from 38.1% to 90.5%, and the antibiotics concentrations ranged from nd~25.25 ng·g-1. The estimated daily intake(EDI) was far below the ADI, and the contribution rate of antibiotics ranged from <0.01% to 29.77%. These results suggest that the intake of aquatic products does not pose an antibiotic exposure risk to human health, but attention is needed for those under treatment with quinolones and macrolide antibiotics while consuming aquatic products. |
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