| 恽 烨,李 威,张银龙,钱 婧,王 月.5-氟尿嘧啶与镉单一及复合污染对三种作物种子萌发的影响[J].农业环境科学学报,2014,33(6):1075-1081. |
| 5-氟尿嘧啶与镉单一及复合污染对三种作物种子萌发的影响 |
| Ecotoxicity of Single and Combined Contamination of 5-fluorouracil and Cd on Seed Germination of Wheat, Chinese Cabbage and Rice |
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| DOI：10.11654/jaes.2014.06.003 |
| 中文关键词: 5-氟尿嘧啶 镉 复合污染 生态毒性 种子发芽 |
| 英文关键词: 5-fluorouracil Cd combined contamination ecotoxicity seed germination |
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| 中文摘要: |
| 采用急性毒性试验方法，研究了典型抗癌药5-氟尿嘧啶和重金属Cd单一及复合污染对小麦、白菜和水稻种子发芽、根伸长及芽伸长的影响。结果表明：单一5-氟尿嘧啶或Cd的浓度与3种作物根伸长和芽伸长抑制率显著相关（P＜0.05）；相对于芽伸长抑制率，根伸长抑制率是更敏感指标；5-氟尿嘧啶对小麦、白菜和水稻种子的根伸长半数抑制浓度（IC50）分别为212.80、102.53、13.30 mg·L-1，Cd对3种作物种子根伸长IC50分别为118.27、23.32、22.21 mg·L-1，3种作物对于两种污染物胁迫的敏感性依次为水稻>白菜>小麦。通过联合毒性试验发现，5-氟尿嘧啶和Cd不同比例浓度复合处理下根伸长的复合抑制率小于各组分单独作用的相加抑制率，对3种作物种子的复合毒性表现为拮抗作用。 |
| 英文摘要: |
| An acute toxicity experiment was designed to examine the effects of single and combined contamination of 5-fluorouracil, a typical anti-cancer drug, and cadmium on seed germination of wheat, Chinese cabbage and rice. Under single contamination, the inhibition rates of root and shoot elongation of three crops significantly correlated with concentrations of 5-fluorouracil and Cd（P<0.05）, and the inhibition rates by 5-fluorouracil and Cd were greater in the roots than in the shoots. The median inhibition concentration（IC50） of 5-fluorouracil and Cd to the root elongation of wheat, Chinese cabbage and rice were 212.80 mg·L-1, 102.53 mg·L-1, and 13.30 mg·L-1, and 118.27 mg·L-1, 23.32 mg·L-1 and 22.21 mg·L-1, respectively. The sensitivity of three crops to 5-fluorouracil and Cd was in sequence of rice>Chinese cabbage>wheat. Combinations of 5-fluorouracil and Cd showed less inhibition to root elongation than the addition of the individuals, implying that combined 5-fluorouracil and Cd had antagonism. |
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