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Joint toxicity of heavy metal Pb and antibiotics to photobacterium
Received:January 30, 2020  
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KeyWord:heavy metals;antibiotics;acute toxicity;concentration addition model (CA);independent action model (IA)
Author NameAffiliationE-mail
LI Meng-han School of Environment, Nanjing Normal University, Nanjing 210023, China  
HE Zi-qi School of Environment, Nanjing Normal University, Nanjing 210023, China  
MIAO Jia-he School of Environment, Nanjing Normal University, Nanjing 210023, China  
WANG Feng-he School of Environment, Nanjing Normal University, Nanjing 210023, China wangfenghe@njnu.edu.cn 
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Abstract:
      Heavy metals are typical inorganic pollutants in water environments. As the detection rate of antibiotics in water has increased, the compound pollution of heavy metals and antibiotics and their effects have become the focus of environmental research. By studying the luminescence inhibition effect of heavy metals and antibiotics on luminescent bacteria, the study tries to understand the toxic effects of heavy metals and antibiotics and provide a theoretical basis for assessing the potential risk of complex pollution of heavy metals and antibiotics in water environments. This article systematically studied the single and combined acute effects of heavy metal Pb and six antibiotics(tetracycline, oxytetracycline, chlorotetracycline, sulfamethazine, sulfamethine, and sulfadiazine) on Vibrio fischeri toxicity, obtaining the half effect concentration of a single pollutant. The combined effect of the binary and ternary compound pollution system composed of heavy metal Pb and antibiotics was discussed. Studies had shown that when Pb coexists with antibiotics, the acute toxicity to luminescent bacteria rised sharply. Therefore, when evaluating the ecological risk of Pb and antibiotic binary or multi-element compound pollution system, the combined toxic effects should be considered.