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| Review on biotransformation and mechanism of fluoroquinolone antibiotics from livestock manure |
| Received:March 01, 2018 Revised:July 03, 2018 |
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| KeyWord:fluoroquinolone;livestock manure;biotransformation;mechanism |
| Author Name | Affiliation | E-mail | | XIA Xiang-qin | College of Environmental Science and Engineering, Guilin University of Technology, Guilin 541006, China
State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China | | | HUANG Cai-hong | State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China | | | XI Bei-dou | College of Environmental Science and Engineering, Guilin University of Technology, Guilin 541006, China
State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China
School of Environmental and Municipal Engineering, Lanzhou Jiaotong University, Lanzhou 730070, China | xibd@craes.org.cn | | TAN Wen-bing | State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China | | | TANG Zhu-rui | College of Environmental Science and Engineering, Guilin University of Technology, Guilin 541006, China
State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012, China | |
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| Abstract: |
| Fluoroquinolone antibiotics (FQs)are veterinary drugs widely used in the livestock husbandry, which can enter the environment with livestock manure and increase the potential for adverse human health impacts and environmental safety. Composting and applying exogenously with efficient degrading bacterium inoculation are considered efficient and green method to remove antibiotics, which reduce the ecological risk of FQs to a minimum level in the environment. Although previous work provided focuses on the remove degradation of FQs, the mechanisms and effect factors of FQs biotransformation have not been studied. In this review article, we highlight the biotransformation of FQs, including degradation conditions, degradation pathways, degradation products and relative residual antibacterial activity. The biotransformation mechanisms of FQs were discussed in detail, and the direction of biotransformation of FQs was also proposed. Overall, this review may provide theoretical basis and technical support for the efficient biodegradation and transformation of FQs and the safe application of livestock manure as resources. |
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